Figure 6

SR141716A has no effect on basal adiponectin secretion, but restores basal level in LPS-treated mature adipocytes . Panel A: Mature adipocytes were treated or not with 200 nM SR141716A for 12 and 24 hours. The medium was assayed for adiponectin using ELISA. The graph shows the mean ± SD of the results from 3 patients (n = 6 for each condition, for each patient). Panel B: Mature adipocytes were treated or not with LPS 1 μg/mL, alone or in combination with 200 nM SR141716A for 24 hours. The medium was assayed for adiponectin using ELISA. The graph shows the mean ± SD of the results from 5 patients (n = 6 for each condition, for each patient). ***P < 0.001, versus control cells. ###P < 0.001, versus LPS-treated cells.