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Figure 3 | Journal of Inflammation

Figure 3

From: Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation

Figure 3

SR141716A decreases the basal MCP-1 secretion, and slightly the LPS-induced MCP-1 secretion in mature adipocytes. Adipocytes were treated with 1 μg/mL LPS and/or not with SR141716A from 50 to 400 nM. MCP-1 secretion was measured in media after 6 hours treatment by ELISA. Results are expressed in percentage, normalised to LPS (100% represents from 2 to 5 ng/mL MCP-1, depending on the patients). The graph shows the mean ± SD of the results from 3 patients (n = 6 for each condition, for each patient). **P < 0.005 and *P < 0.05, versus control cells.

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