Figure 1From: Tyrosine kinases in rheumatoid arthritisTyrosine kinases involved in the signal transduction pathways in rheumatoid arthritis. Various tyrosine kinases have important roles in the pathogenesis of RA and these kinases are possible targets for the anti-RA strategy. MAP3K: MAPK kinase kinases, MKK: MAPK kinases, MAPK: mitogen-activated protein kinase, ERK: extracellular signal-regulated kinases, Syk: spleen tyrosine kinase, NF-κB: nuclear factor κ-light-chain-enhancer of activated B cells, IKK: IκB kinase, JAK: the Janus kinases, STAT: signal transducers and activators of transcription.Back to article page