Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease

Journal of Inflammation

Table 6 Risk factors affecting hypertension and LVMI in CKD patients based on multiple linear regression analysis

Dependent variables		ß	Unstandardized B	95%CI for ß	P-value
Indexed SBP	Serum urea	0.20	7.36	1.55-8.63	0.04*
	Serum creatinine	0.02	1.62	5.76-9.01	0.63
	ACE activity	0.01	0.07	0.09-0.23	0.37
	D-allele	0.09	0.90	0.96-1.32	0.35
	C-allele	0.32	8.35	1.53-8.65	0.04*
	hs-CRP	0.32	9.52	1.54-9.61	0.04*
	CK-MB	0.25	7.35	1.65-7.68	0.02*
LVMI	D-allele	0.01	1.23	12.40-15.36	0.53
	C-allele	0.08	2.45	13.74-18.66	0.66
	hs-CRP	0.09	1.27	7.17-9.71	0.58
	CK-MB	0.30	9.63	1.64-7.61	0.04*
	TG	0.66	6.50	0.98-2.50	0.04*
	Urea	0.81	5.42	1.76-8.17	0.02*
	Creatinine	0.51	5.41	0.99-9.83	0.03*
	Indexed DBP	0.63	5.63	0.46-1.44	0.0001**

ACE = angiotensin converting enzyme, hs-CRP = high sensitivity c-reactive protein, CK-MB = creatine kinase-MB fraction, TG = triglycerides, DBP = diastolic blood pressure, CI = Confidence Interval. **P < 0.01 or *P < 0.05 was considered significant.

ISSN: 1476-9255