Figure 1

In vitro inhibitory effect of antibiotics towards PAF-CPT enzyme activity of rabbit leukocytes. The amounts of each drug that induced approximately fifty to one hundred inhibitory effects against PAF-CPT specific activity are expressed as μg of each bioactive compound added in the assay mixture/μL of assay volume. PAF-CPT specific activity of rabbit leukocytes is expressed as nmol of produced PAF/min/mg of total protein in assay. Control signifies PAF-CPT specific activity of rabbit leukocytes in the absence of any drug. Results are the average of three independent determinations using different enzyme preparations performing duplicate samples. (* p < 0.05 compared to control). PAF-CPT: Cholinephosphotransferase of PAF.