Figure 5
From: T-bet controls severity of hypersensitivity pneumonitis
Increased collagen in lungs of T-bet mice exposed to S. rectivirgula. C57BL/6 or T-bet-/- mice (5/group) were intranasally exposed to S. rectivirgula (150 μg) or saline for 3 weeks. The right lung lobe was removed from mice and the collagen content was determined as described in methods. The results are expressed as amount of collagen/right lung lobe and represent the average+/- SD in each group of mice. *p < 0.05; T-bet KO mice exposed to S. rectivirgula compared to WT mice exposed to S. rectivirgula.