Table 4 Semi-quantitative evaluation (mean ± SEM) of renal PCNA and vimentin expressions in male and female rats in control, after ischemia (D0) and ischemia followed by 1 (D1) or 5 days (D5) of reperfusion
From: Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair
Male | Female | |||
|---|---|---|---|---|
PCNA index (%) | ||||
Control | 1.5 ± 1.2 | 0.8 ± 0.9 | ||
D0 | 5.4 ± 0.7 | 5.1 ± 0.8 | ||
D1 | 80.0 ± 3.1* | 10.6 ± 1.1 | ||
D5 | 41.4 ± 2.1* | 13.3 ± 1.1 | ||
Vimentin (%) | ||||
Control | 0 | 0 | ||
D0 | 0.3 ± 0.7 | 0.2 ± 0.6 | ||
D1 | 14.2 ± 1.7* | 5.0 ± 1.3 | ||
D5 | 9.1 ± 0.8* | 2.9 ± 0.6 | ||
*p <0.0001 vs. Female. | ||||
TSPO | Proximal tubule | Distal tubule | ||
Male | Female | Male | Female | |
Control | 0 | 0 | +++ | +++ |
D0 | 0 | 0 | +++ | +++ |
D1 | + | 0 | +++ | +++ |
D5 | 0 | 0 | +++ | +++ |