Table 3 Plasma adipokines and other parameters before and after 8-week treatment with fluticasone in 11 asthmatics.
From: Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma
Before treatment | After treatment | p-value | |
|---|---|---|---|
Resistin (ng/l)/BMI (m2/kg) | 0.4 [0.3 - 0.5] | 0.4 [0.4-0.5] | 0.722 |
Leptin (ng/l)/BMI (m2/kg) | 0.5 [0.4 - 1.1] | 0.7 [0.2-1.0] | 0.722 |
Adiponectin (ng/l)/BMI (m2/kg) | 154.4 ± 20.1 | 146.4 ± 21.0 | 0.271 |
Adipsin (ng/l)/BMI (m2/kg) | 27.5 ± 1.5 | 24.9 ± 1.8 | 0.026 |
ECP (μg/l) | 16.0 [8.5 - 46.8] | 12.4 [6.2 - 21.4] | 0.026 |
EPX (μg/l) | 47.2 [28.8 - 68.4] | 22.3 [16.6 - 45.1] | 0.013 |
MPO (μg/l) | 218.6 [163.5 - 409.1] | 199.7 [144.7 - 266.8] | 0.534 |
FEV1(% pred) | 85 ± 4.0 | 95 ± 5.5 | 0.032 |
JBr,NO (nl/s) | 3.6 ± 0.4 | 0.6 ± 0.1 | <0.001 |
CAlv (ppb) | 1.5 ± 0.6 | 1.3 ± 0.1 | 0.705 |
Symptom score | 6.0 [4.0 - 10.0] | 0 [0.0 - 0.0] | 0.005 |