Figure 3
From: Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils
The effect of HDAC inhibitors apicidin (A), MC1293 (B) and MS-275 (C) on apoptosis in eosinophils in the absence of survival-prolonging cytokines (ie. spontaneous apoptosis). Apoptosis was assessed by flow cytometry measuring the relative DNA fragmentation in propidium iodide-stained cells. **P < 0.01 and ***P < 0.001 as compared with the respective control in the absence of HDAC inhibitors. Mean ± S.E.M. of 5-6 independent determinations using cells from different donors.