The effect of caspase inhibitors on TSA (330 nM)-induced human eosinophil apoptosis. The concentrations used were: Q-Vd-Oph (20 μM), Z-Asp-CH2-DCB and IETD-CHO (100 μM) and Z-D(OMe)QMD(OMe)-FMK and Z-VE(OMe)ID(OMe)-FMK (200 μM). Apoptosis was assessed by the relative DNA fragmentation assay. Each data point represents the mean ± SEM of 6-7 independent determinations using eosinophils from different donors. * indicates p < 0.05 and *** p < 0.001 as compared with the respective control in the absence of caspase inhibitors.