Table 3 Therapies during the first 6 hours in the ED and from 7 to 72 hours in the ICU by lactate clearance quartile.
| Â | Quartile 1 N = 55 | Quartile 2 N = 55 | Quartile 3 N = 55 | Quartile 4 N = 55 | P-value |
|---|---|---|---|---|---|
Therapies in first 6 hours | |||||
   Antibiotics (%) | 72.2 | 77.5 | 72.1 | 75.0 | 0.95 |
   Appropriate Antibiotics (%) | 86.3 | 77.5 | 90.7 | 88.9 | 0.59 |
   Fluids (mL) | 4531.2 ± 2745.3 | 4263.5 ± 2872.9 | 4266.8 ± 3449.5 | 3741.7 ± 3136.4 | 0.27 |
   Transfusion (%) | 54.6 | 41.8 | 26.4 | 43.6 | 0.27 |
   Vasopressor (%) | 50.9 | 36.4 | 27.3 | 14.6 | <0.01 |
   Inotrope/dobutamine (%) | 5.5 | 3.6 | 9.1 | 12.7 | 0.29 |
   Mechanical ventilation (%) | 74.6 | 50.9 | 58.2 | 38.2 | <0.01 |
Therapies from 7 to 72 hours | |||||
   Antibiotics (%) | 95.0 | 93.9 | 100 | 97.0 | 0.50 |
   Fluids (mL) | 8817.2 ± 5818.1 | 9666.7 ± 6555.2 | 10329.8 ± 6866.6 | 7141.9 ± 4097.8 | 0.06 |
   Transfusion (%) | 23.6 | 20.0 | 20.0 | 27.3 | 0.77 |
   Vasopressor (%) | 47.3 | 47.3 | 30.9 | 18.2 | <0.01 |
   Inotrope/dobutamine (%) | 10.9 | 14.6 | 9.1 | 12.7 | 0.83 |
   Mechanical ventilation (%) | 12.7 | 14.6 | 7.3 | 7.3 | 0.48 |