Skip to main content

Table 1 Patient characteristics.

From: Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock

No. Patients 220
Age (years) 65.0 ± 17.1
Male:Female (%) 54.1:45.9
Time from ED arrival to enrollment (hours) 1.6 ± 2.1
Length of hospital stay (days) 13.9 ± 16.6
Vital signs and hemodynamic variables  
   Temperature (°C) 36.3 ± 2.8
   Heart rate (beats per min) 117.1 ± 30.1
   Systolic blood pressure (mm Hg) 107.5 ± 36.2
   Mean arterial pressure (mm Hg) 74.8 ± 25.7
   Shock index (heart rate/systolic blood pressure) 1.2 ± 0.5
   Respiratory rate (breaths per min) 31.5 ± 11.1
   CVP (mm Hg) 5.1 ± 8.5
   ScvO2 (%) 49.2 ± 12.6
Laboratories
   White blood cells (×103 per mm3) 14.0 ± 9.0
   Hemoglobin (g/dL) 11.4 ± 2.7
   Platelets (×103 per μL) 211.5 ± 122.0
   Creatinine (mg/dL) 2.9 ± 2.0
   Glucose (mg/dL) 259.4 ± 327.8
   Anion gap (mEq/L) 21.5 ± 8.0
   Total bilirubin (mg/dL) 1.5 ± 2.1
   Albumin (g/dL) 2.8 ± 0.7
   Lactate (mmol/L) 7.4 ± 4.6
   Lactate clearance (%) 35.5 ± 43.1
Septic shock (%) 55.0
Culture positive (%) 65.6
Blood culture positive (%) 37.1
Organ dysfunction scores
   APACHE II 21.5 ± 7.0
   SAPS II 49.8 ± 11.0
   MODS 7.6 ± 3.1
   SOFA 6.5 ± 2.9
Source of infection (%)  
   Pneumonia 39.5
   Urinary tract infection 13.2
   Intra-abdominal 4.1
   Other 43.2
Comorbidities (%)
   Chronic obstructive pulmonary disease 16.4
   Chronic renal insufficiency 20.9
   Congestive heart failure 30.9
   Coronary artery disease 22.7
   Diabetes mellitus 30.5
   Hypertension 67.3
   Liver disease 21.4
Outcome (%)
   In-hospital mortality 35.0
   28-day mortality 36.4
   60-day mortality 42.7
  1. Vital signs, hemodynamic variables, laboratories and organ dysfunction scores represent baseline values at patient enrollment. ED - emergency department; CVP - central venous pressure; ScvO2 - central venous oxygen saturation; Acute Physiology and Chronic Health Evaluation (APACHE) II; Simplified Acute Physiology Score (SAPS) II; Multiple Organ Dysfunction Score (MODS); Sequential Organ Failure Assessment (SOFA).