Skip to main content
Figure 1 | Journal of Inflammation

Figure 1

From: Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock

Figure 1

Mean biomarker levels averaged over 72 hours based on lactate clearance quartile. The mean levels of pro-inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α), intercellular adhesion molecule-1 (ICAM-1), and high mobility group box-1 (HMGB-1); anti-inflammatory markers interleukin-1 receptor antagonist (IL-1ra) and interleukin-10 (IL-10); coagulation marker D-Dimer; and apoptosis marker Caspase-3 are significantly lower over 72 hours with higher lactate clearance quartiles.

Back to article page