Figure 7
Neutrophil accumulation in heart tissue: Intravenous administration of lipopolysaccharide (LPS) in rats causes accumulation of neutrophils in heart tissue as detected by myeloperoxidase (MPO) activity in atrial slices 24 hours after LPS infusion. Intravenous treatment with a carboxamide derivative, feG(NH2), at the time of LPS infusion, dose-dependently inhibited MPO in atrial slices. (mean ± sem, n = 4 to 8). Adapted from [46].