Inhibition of IL-13, IL-10 and IL-4 cytokine release from MLRs by Didox and Trimidox. The levels of IL-13, IL-10 and IL-4 were determined using the Searchlight multiplex assay system from minor (open square) or major (filled square) mixed lymphocyte reactions. NC: Normal control, AC: Activated control. The results shown represent data obtained in triplicate from two independent experiments (n = 3-6). (*p < 0.05, ** p < 0.001 indicates a significant difference compared to activated control (AC), ANOVA + the Bonferroni test.