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Table 1 Effect of albumin on the changes in gene expression over a 2 h incubation

From: The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells

mRNA Fold change over 2 h % change in the presence of 1% albumin
IL-8 87 ± 8*** +540 ± 44%***
IL-1β 24 ± 4*** +6000 ± 60%***
TNFα 6.1 ± 0.9*** +920 ± 50%***
HIF-1α 2.4 ± 0.8** -10 ± 20%
NFKB1 [p50] 3.5 ± 0.9** +40 ± 18%
Omentin/intelectin 0 ± 1 0 ± 20%
  1. Explants of human omental adipose tissue were incubated for 2 h in buffer without or with 1% albumin. The basal data are shown as the mean ± SEM for eight experiments of the ratio of each mRNA at 2 h to that at the start of the incubation. The effects of the albumin are the mean ± SEM of the paired percentage differences. Significant effects of the 2-h incubation and of albumin or serum are indicated as follows: * P < 0.05, ** P < 0.025 and *** P < 0.01