Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome: a cross sectional study

Rogowski, Ori; Shapira, Itzhak; Bassat, Orit Kliuk-Ben; Chundadze, Tamar; Finn, Talya; Berliner, Shlomo; Steinvil, Arie

doi:10.1186/1476-9255-7-35

Table 3 Metabolic syndrome components ordered according to the strength of the association to each inflammatory biomarker.

From: Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome: a cross sectional study

Inflammatory variable	Gender	Variable	Non-standardized Coefficients		Significance	Partial Correlation
			B	S.E.
Log(hs-CRP)	Men	Waist	0.013	0.001	< 0.001	0.274
(R² = 0.17)		HDL	-0.004	0.001	< 0.001	-0.095
		Log(TG)	0.111	0.026	< 0.001	0.052
		DBP	0.003	0.001	0.002	0.038
		Glucose	0.001	0.001	0.045	0.024
		SBP	0.000	0.001	0.571	-0.007
(R² = 0.33)	Women	Waist	0.016	0.001	< 0.001	0.331
		Log(TG)	0.459	0.038	< 0.001	0.189
		HDL	-0.002	0.001	< 0.001	-0.057
		Glucose	0.002	0.001	0.062	0.030
		SBP	0.001	0.001	0.104	0.026
		DBP	0.001	0.001	0.382	0.014
Log(ESR)	Men	Waist	0.003	< 0.001	< 0.001	0.091
(R² = 0.07)		HDL	-0.002	< 0.001	< 0.001	-0.045
		Log(TG)	0.062	0.021	0.003	0.037
		SBP	< 0.001	< 0.001	0.059	-0.024
		Glucose	< 0.001	< 0.001	0.689	-0.005
		DBP	< 0.001	0.001	0.584	0.007
(R² = 0.07)	Women	Waist	0.003	< 0.001	< 0.001	0.114
		Log(TG)	0.105	0.024	< 0.001	0.072
		HDL	< 0.001	< 0.001	0.100	-0.027
		SBP	< 0.001	< 0.001	0.370	-0.015
		Glucose	< 0.001	0.001	0.507	-0.011
		DBP	< 0.001	0.001	0.746	0.005
Fibrinogen	Men	Waist	0.873	0.074	< 0.001	0.141
(R² = 0.14)		DBP	0.560	0.116	< 0.001	0.059
		HDL	-0.250	0.070	< 0.001	-0.043
		SBP	-0.210	0.067	0.002	-0.038
		Glucose	0.096	0.077	0.210	0.015
		Log(TG)	-3.648	3.364	0.278	-0.013
(R² = 0.12)	Women	Waist	1.282	0.095	< 0.001	0.214
		DBP	0.363	0.181	0.045	0.032
		Log(TG)	7.253	5.106	0.156	0.023
		Glucose	-0.157	0.110	0.153	-0.023
		HDL	-0.086	0.068	0.202	-0.021
		SBP	-0.103	0.100	0.303	-0.017
WBCC	Men	Log(TG)	1.153	0.097	< 0.001	0.146
(R² = 0.12)		Waist	0.019	0.002	< 0.001	0.109
		Glucose	-0.008	0.002	0.001	-0.042
		DBP	0.010	0.003	0.002	0.038
		SBP	0.005	0.002	0.013	0.031
		HDL	-0.004	0.002	0.047	-0.025
(R² = 0.13)	Women	Log(TG)	1.604	0.147	< 0.001	0.177
		Waist	0.012	0.003	< 0.001	0.071
		HDL	-0.005	0.002	0.011	-0.042
		SBP	0.007	0.003	0.014	0.041
		Glucose	-0.004	0.003	0.180	-0.022
		DBP	0.002	0.005	0.711	0.006

*Criteria for the metabolic syndrome components are defined in the text.
**All models were adjusted in addition to the different components of the MetS, to age, history of proven atherothrombotic disease, smoking status, alcohol consumption, level of physical activity and medication such as ACE inhibitors, Angiotensin II receptor blockers, statins, fibrates and aspirin, as well as hormone replacement therapy or oral contraceptives in females.
***Abbreviations: hs-CRP = high sensitivity C-reactive protein; ESR = erythrocyte sedimentation rate; WBCC = white blood cell count; HDL = high density lipoprotein; TG = triglycerides; DBP = diastolic blood pressure, SBP = systolic blood pressure.

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ISSN: 1476-9255

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