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Figure 1 | Journal of Inflammation

Figure 1

From: Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice

Figure 1

Severe thermal injury at a remote distal site attenuates ear-hole wound closure and tissue regeneration in MRL/MpJ mice. (A) Time course of ear-hole closure in thermally injured and solely ear-hole wounded MRL/MpJ mice. Data represent mean percent ear-hole closure ± 1 SD of ten animals in each group. (B) Macroscopic changes in ear-hole healing control and thermally injured mice. Representative photographs of the ear-hole wound sites at the indicated time post injury. The arrow points to a ear-hole wound that is 85% closed. (C) Representative histological sections of ear wound margin tissue 9 and 21 days after full-thickness third degree thermal injury (original magnification, × 40)

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