Figure 20

Effect of GW0742 on liver injury. Administration of zymosan resulted in significantly increased levels of plasma AST (A), ALT (B), bilirubin (C) and alkaline phosphatase (D). GW0742 treatment significantly reduced all these parameters in zymosan treated mice. Data are mean ± standard deviation from n = 10 mice for each group. *P < 0.01 vs sham, °P < 0.01 vs zymosan + vehicle.