Comparison of LPS induced TNFalpha secretion by human peripheral blood mononuclear cells versus human mature adipocytes. Human mature adipocytes and peripheral blood mononuclear cells were treated with a LPS dose-response (5, 10 ng/mL and 1 μg/mL). TNFα concentrations in medium (pg/mL) were determined at 6 hours. Plating was 8 × 104 for macrophages and 3 × 104 for adipocytes. The graph represents the mean ± SE of the results from one patient (n = 6 for each condition) for each cell type, representative of two experiments on two different patients (macrophages) and representative of three experiments on three different patients (adipocytes).