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Figure 4 | Journal of Inflammation

Figure 4

From: Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation

Figure 4

Schematic representation of the PRCP-dependent PK activation pathway on LPS pretreated endothelial cells. PRCP: prolylcarboxypeptidase; PK: prekallikrein; HK: high molecular weight kininogen; BK: bradykinin; FXII: factor XII (Hageman factor); FXIIa: activated factor XII. ↑ Indicates an increase, and the thickness of the arrow illustrates the extent of an increase.

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