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Figure 2 | Journal of Inflammation

Figure 2

From: Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway

Figure 2

Effect of IL-8 on phosphorylation of Akt in human adipocytes. After treatment with IL-8 (100 nM) for the indicated period (A), human adipocytes were stimulated with insulin (100 nM) for 10 min. The phosphorylation of Akt induced by insulin (100 nM) was analyzed by Western blot. For the experiments with inhibitors (B), 0.1% DMSO was added as vehicle control, and PD98059 (50 μM) or SB203580 (50 μM) was added 2 h before stimulation with insulin (100 nM). The data are representative of three different experiments (Means ± SD). * P < 0.01, ** P < 0.05

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