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Figure 2 | Journal of Inflammation

Figure 2

From: Modulation of expression and cellular distribution of p21 by macrophage migration inhibitory factor

Figure 2

rMIF rescues cells from basal and SNP induced apoptosis. The effect of rMIF on apoptosis of MDF was examined using cytometric detection of annexin V/PI dual labeling. MIF-/- MDF demonstrated increased rates of spontaneous apoptosis which was reduced following treatment with 100 ng/ml rMIF. Similarly, rMIF treatment abrogated SNP (0.25 mM) induced apoptosis in both MIF-/- and wt MDF, (N = 3, * P < 0.05).

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