Figure 6From: CCR5 signalling, but not DARC or D6 regulatory, chemokine receptors are targeted by herpesvirus U83A chemokine which delays receptor internalisation via diversion to a caveolin-linked pathwayU83A specific induction of co-localisation of CCR5 with caveolin-1. Localisation of CCR5 and caveolin-1 was monitored by confocal microscopy, in absence of stimulation (a), when stimulated with 30 minutes with 100 nM CCL4 (b) or U83A (c). CCR5 is labelled with antibody linked to FITC (green) and caveolin-1 with TRITC (red), co-localisation appears as yellow.Back to article page