Figure 5

IL-1β secretion induced by exposure to glycol-derived compounds. IL-1β secretion (ELISA, in pg/ml) of human T24 cells exposed during 48 hours to increasing osmolarities (300, 600, 900 mOsm) of different compounds: A) Mannitol (300 mOsm [31.969–75.141]; 600 mOsm [59.164–80.941]; 900 mOsm [125.69–154.45]); B) Propylene Glycol (300 mOsm [31.969–75.141]; 600 mOsm [59.674–105.90]; 900 mOsm [97.915–195.67]); C) Glycerol (300 mOsm [31.969–75.141]; 600 mOsm [64.276–167.78]; 900 mOsm [66.748–251.01]). For each group, the horizontal bar is the median. Upper values represent the global p-values (Kruskal-Wallis test). The p-value given by the Tukey test above a stripchart indicates the result of the comparison of this group versus control. CI at 95% are given in parentheses (n = 5).