Figure 5From: Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosisSchematic representation of the roles of NO, ONOO-, & cGMP in macrophage apoptosis. NO and O2•- combine to form ONOO- which promotes macrophage apoptosis. Agents that act to elevate cGMP are able to limit ONOO--induced apoptosis.Back to article page