Figure 1
From: Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis
NO generation by DETA/NO and GEA-3162 measured by isolated NO electrode A – NO liberated by DETA/NO (300 μM) recorded for 30 min (n = 6). B – GEA-3162 (300 μM) failed to liberate free NO in solution except in the presence of SOD. Each addition of SOD is added approximately 3 – 5 min following the previous addition. The concentration of NO liberated in the presence of SOD was unchanged by MDMϕ (n = 3). Arrows indicate addition of Hb. C – In the presence of 500 U.ml-1 SOD, GEA-3162 (300 μM) liberated NO over a period of approximately 4 h (n = 6).