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Table 1 CIA Treatment Regimen

From: Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis

Group

N

Treatment

Dose

Group 1

10

control mAb

1 mg/week

Group 2

10

Anti-IL-6

1 mg/week

Group 3

10

Anti-IL-6

5 mg/week

  1. Mice received weekly IP injections for 10 weeks. Groups 1 and 2 received 200 μL sterile PBS containing the required dose. Group 3 received 1 mL sterile PBS (500 μL on 2 consecutive days) containing the required dose of anti-IL-6.