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Figure 3 | Journal of Inflammation

Figure 3

From: The tripeptide feG inhibits leukocyte adhesion

Figure 3

Effects of feG on the adhesion of carrageenan neutrophils to heparin, IgG, fibrinogen, fibronectin and vitronectin. Three different types of results are summarized: 1) the effects of antigen challenge (Ag); 2) the effects of in vivo treatment with feG (i.p. feG); and 3) the effects of ex vivo feG (open column). The adhesion, expressed as optical density (O.D.) for 1 million cells, is shown in the presence of PAF (10-9M) alone (black column), and in the presence of PAF and ex vivo feG (open column). The adhesion in the presence of ex vivo feG is the average adhesion for 10-10M to 10-12M feG added to the cells in the 96-well plate bars. Results are shown for four groups of animals: unsensitized (Unsens); unsensitized treated intraperitoneally with feG 18 h before harvesting the cells (Unsens + i.p. feG); antigen-challenged sensitized (Ag); and antigen-challenged sensitized treated intraperitoneally with feG 18 h before harvesting the cells (Ag + i.p. feG). Mean ± SEM; p < 0.05. # less than corresponding unsensitized group; χ greater than unsensitized group; * less than corresponding control (PAF alone); δ greater than no i.p. feG; X greater than corresponding unsensitized group. n ≥ 4 for each group of cells.

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