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Table 1 Differentially expressed genes between adult and cord monocytes at specific time points. T = time (min) at which the sample was taken. Numbers indicate corrected expression values.

From: A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells

     Adult Adult Adult Cord Cord  
  Genbank # Symbol Gene Description T = 0 t = 45 t = 120 t = 0 t = 45 t = 120
Apoptosis          
  NM_033423 CTLA1 Similar to granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 317 419 299 199 193 264
  AB037796 PDCD6IP Programmed cell death 6 interacting protein 75 155 68 79 70 81
  NM_024969 TAIP-2 TGFb-induced apoptosis protein 2 63 113 107 53 68 116
  NM_003127 SPTAN1 Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 713 842 1171 724 824 2093
Protein synthesis, processing, degradation          
  AK001313 RPLP0 Ribosomal protein, large, P0 704 1465 947 703 756 669
  NM_006799 PRSS21 Protease, serine, 21 (testisin) 204 789 457 169 360 400
  NM_003774 GALNT4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) 576 651 648 528 378 578
  AK057790   cDNA FLJ25061 fis, clone CBL04730 245 373 302 244 215 200
  NM_004223 UBE2L6 Ubiquitin-conjugating enzyme E2L 6 128 191 146 108 99 109
  NM_014710 GPRASP1 KIAA0443 gene product 122 182 106 113 119 95
  NM_021090 MTMR3 Myotubularin related protein 3 109 171 137 108 87 138
  AF339824 HS6ST3 Heparan sulfate 6-O-sulfotransferase 3 89 112 91 94 46 76
  NM_012180 FBXO8 F-box only protein 8 40 67 42 45 33 43
  U66589 RPL5 Ribosomal protein L5 34 48 37 30 26 36
  NM_001870 CPA3 Carboxypeptidase A3 (mast cell) 183 495 610 146 949 756
  NM_006145 DNAJB1 DnaJ (Hsp40) homolog, subfmaily B, member 1 179 277 408 168 299 745
  AK025547 MRPL30 Mitochondrial ribosomal protein L30 83 118 126 81 101 211
  NM_000439 PCSK1 Proprotein convertase subtilisin/kexin type 1 39 55 53 40 78 88
Cell/Organism Movement          
  NM_002067 GNA11 Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 555 870 607 540 468 664
  NM_002465 MYBPC1 Myosin binding protein C, slow type 81 140 154 88 80 161
  NM_003275 TMOD Tropomodulin 276 151 481 257 344 503
  AK026164 MYL6 Myosin, light polypeptide 6, alkali, smooth muscle and non-muscle 7 6 48 5 16 11
Small Molecule Interactions          
  NM_006030 CACNA2D2 Calcium channel, voltage-dependent, alpha 2/delta subunit 2 670 1390 1021 641 639 946
  AK025170 SFXN5 FLJ21517 fis, clone COL05829 431 537 437 405 295 374
  NM_021097 SLC8A1 Solute carrier family 8 (sodium/calcium exchanger), member 1 396 456 458 412 276 369
Signal Transduction          
  NM_032144 RAB6C RAB6C 827 1658 1307 626 773 1251
  NM_001982 ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 603 1375 671 555 584 643
  AK026479 SNX14 Sorting nexin 14 682 1207 879 624 567 883
  NM_018979 PRKWNK1 Protein kinase, lysine deficient 1 451 813 782 516 480 792
  NM_004811 LPXN Leupaxin 329 539 445 323 298 503
  BC005365   clone IMAGE:3829438, mRNA, partial cds 257 418 275 275 275 206
  NM_004723 ARHGEF2 Rho/rac guanine nucleotide exchange factor (GEF) 2 215 300 228 197 176 186
  AF130093 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 237 285 275 221 171 223
  AK000383 MKPX Mitogen-activated protein kinase phosphatase x 218 221 244 233 126 197
  NM_022304 HRH2 Histamine receptor H2 45 121 86 42 74 79
  NM_030753 WNT3 Wingless-type MMTV integration site family member 3 105 117 92 109 63 81
  AB024574 GTPBP2 GTP binding protein 2 89 90 99 74 57 92
  NM_002836 PTPRA Protein tyrosine phosphatase, receptor type, A 8 6 80 6 16 28
  NM_003656 CAMK1 Calcium/calmodulin-dependent protein kinase I 4940 10131 4446 4785 4907 7190
Cellular Metabolism & Cell Division          
  NM_006170 NOL1 Nucleolar protein 1 (120 kD) 575 1815 1021 499 896 1093
  AL133115 COVA1 Cytosolic ovarian carcinoma antigen 1 1381 1294 848 1309 658 808
  D86962 GRB10 Growth factor receptor-bound protein 10 619 906 200 609 512 179
  NM_005628 SLC1A5 Solute carrier family 1 (neutral amino acid transporter), member 5 338 801 600 311 397 524
  D17525 MASP1 Mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) 372 654 43 361 325 55
  NM_016518 PIPOX Pipecolic acid oxidase 240 545 330 221 293 286
  NM_012157 FBXL2 F-box and leucine-rich repeat protein 2 274 501 374 249 277 298
  NM_018446 AD-017 Glycosyltransferase AD-017 301 369 337 288 223 327
  NM_001609 ACADSB Acyl-Coenzyme A dehydrogenase, short/branched chain 354 368 325 273 211 276
  NM_001647 APOD Apolipoprotein D 259 358 289 261 202 205
  NM_012113 CA14 Carbonic anhydrase XIV 218 356 279 251 194 270
  AB067472 DKFZP434L1435 KIAA1885 protein 150 213 186 166 119 163
  NM_002916 RFC4 Replication factor C (activator 1) 4 (37 kD) 102 177 119 105 86 132
  NM_004889 ATP5J2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 106 147 76 102 76 62
  AK057066   cDNA FLJ32504 fis, clone SMINT1000016, weakly similar to 2-hydroxyacylsphingosine 1b 69 121 126 64 75 84
  AK021722 AGPAT5 Lysophosphatidic acid acyltransferase, epsilon 37 71 48 42 39 46
  NM_003664 AP3B1 Adaptor-related protein complex 3, beta 1 subunit 34 52 29 37 24 30
  AF146760 Sept10 Septin 10 22 36 23 26 16 28
  NM_004910 PITPNM Phosphatidylinositol transfer protein, membrane-associated 2611 2809 2410 2974 4590 2675
  NM_018216 FLJ10782 Pantothenic acid kinase 10 9 10 9 18 15
  NM_001714 BICD1 Bicaudal D homolog 1 (Drosophila) 230 562 407 197 447 691
  AK054944 LENG5 Leukocyte receptor cluster (LRC) member 5 67 100 91 78 74 158
Gene Expression          
  NM_005088 DXYS155E DNA segment on chromosome X and Y (unique) 155 expressed sequence 4857 3489 3214 5177 2241 2725
  NM_006298 ZNF192 Zinc finger protein 192 552 988 761 537 578 820
  NM_004991 MDS1 Myelodysplasia syndrome 1 401 691 480 390 361 420
  NM_021784 HNF3B Hepatocyte nuclear factor 3, beta 320 632 367 347 361 391
  AF153201 LOC58502 C2H2 (Kruppel-type) zinc finger protein 288 532 335 244 297 324
  NM_025212 IDAX Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex) 297 490 311 303 254 241
  AK022962 PBX1 Pre-B-cell leukemia transcription factor 1 237 456 326 245 261 345
  NM_017617 NOTCH1 Notch-1 homolog 309 358 353 324 208 370
  NM_001451 FOXF1 Forkhead box F1 165 347 306 177 208 328
  NM_007136 ZNF80 Zinc finger protein 80 (pT17) 199 269 203 205 143 177
  NM_021975 RELA V-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene 184 221 139 150 124 122
  NM_031214 TARDBP TAR DNA binding protein 76 154 109 74 91 90
  NM_014007 ZNF297B Zinc finger protein 297B 109 137 122 109 77 111
  NM_014938 MONDOA Mlx interactor 74 90 92 69 53 86
  NM_005822 DSCR1L1 Down syndrome critical region gene 1-like 1 45 80 30 40 27 26
  NM_004289 NFE2L3 Nuclear factor (erythroid-derived 2)-like 3 73 63 41 64 39 38
  NM_054023 SCGB3A2 Secretoglobin family 3a, member 2 37 59 45 43 34 49
  NM_012107 BP75 Bromodomain containing protein 75 kDa human homolog 44 51 34 37 22 30
  NM_007212 RNF2 Ring finger protein 2 48 40 30 45 18 26
  D89859 ZFP161 Zinc finger protein 161 homolog (mouse) 500 596 4280 458 481 6699
  NM_014335 CRI1 CREBBP/EP300 inhibitory protein 1 52 84 86 57 72 196
Immune Function          
  NM_014889 MP1 Metalloprotease 1 (pitrilysin family) 352 401 398 379 260 351
  NM_014312 CTXL Cortical thymocyte receptor (X. laevis CTX) like 386 370 375 392 224 299
  NM_002053 GBP1 Guanylate binding protein 1, interferon-inducible, 67 kD 259 369 334 245 214 251
  NM_005356 LCK Lymphocyte-specific protein tyrosine kinase 186 206 187 235 124 181
  NM_000564 IL5RA Interleukin 5 receptor, alpha 112 106 124 121 63 150
  NM_001311 CRIP1 Cysteine-rich protein 1 (intestinal) 45 31 39 49 60 43
  NM_002984 SCYA4 Small inducible cytokine A4 MIP1B 492 2001 2483 517 1523 3897
  NM_002983 SCYA3 Small inducible cytokine A3 MIP1A 248 1798 2207 185 1364 3673
  NM_014443 IL17B Interleukin 17B 663 696 681 706 703 1155
  NM_006018 HM74 Putative chemokine receptor-GTP-binding protein 13 25 19 15 26 34
Miscellaneous Functions          
  AB033041 VANGL2 Vang, van gogh-like 2 (Drosophila) 983 1246 1351 981 796 1304
  AK021444 POSTN Periostin, osteoblast specific factor 569 917 789 522 479 629
  NM_003691 STK16 Serine/threonine kinase 16 403 777 458 395 348 393
  NM_006438 COLEC10 Collectin sub-family member 10 (C-type lectin) 284 762 500 260 351 528
  AK057699   FLJ33137 fis, clone UTERU1000077 375 637 613 369 392 616
  NM_017671 C20orf42 Chromosome 20 open reading frame 42 362 557 551 280 323 478
  AK054683 DCLRE1C DNA cross-link repair 1C 486 555 574 476 293 515
  NM_033060 KAP4.10 Keratin associated protein 4.10 210 245 197 154 123 172
  AF319045 CNTNAP2 Contactin associated protein-like 2 112 215 173 120 113 176
  NM_001046 SLC12A2 Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 158 148 184 146 86 161
  NM_016279 CDH9 Cadherin 9, type 2 (T1-cadherin) 77 112 69 65 51 64
  NM_014208 DSPP Dentin sialophosphoprotein 60 90 64 57 53 59
  NM_015669 PCDHB5 Protocadherin beta 5 92 83 62 98 42 47
  AK023198 OPRK1 Opioid receptor, kappa 1 58 76 41 48 46 38
  NM_018240 KIRREL Kin of IRRE like (Drosophila) 60 75 47 66 43 46
  AK056781 ROCK1 Rho-associated, coiled-coil containing protein kinase 1 54 62 42 47 41 42
  NM_022123 NPAS3 Basic-helix-loop-helix-PAS protein 17 22 9 16 12 13
  NM_001246 ENTPD2 Ectonucleoside triphosphate diphosphohydrolase 2 3438 3272 3731 3767 3590 6309
Unknown Function          
  AK056884   FLJ32322 fis, clone PROST2003577 2007 2878 2008 1825 1548 1958
  NM_017812 FLJ20420 Coiled-coil-helix-coiled-coil-helix domain containing 3 1105 1915 1370 1125 940 1358
  AJ420459 LOC51184 Protein x 0004 661 1579 881 603 771 768
  BC011575   Similar to RIKEN cDNA 0610031J06 gene, clone IMAGE:4639306 974 1556 1412 1020 844 1261
  AK057357 FLJ32926 DKFZp434D2472 1188 1378 1159 1043 515 1136
  NM_025019 TUBA4 tubulin, alpha 4 1446 1173 1330 1477 782 1366
  AK023150   FLJ13088 fis, clone NT2RP3002102 798 1087 905 845 564 785
  NM_017833 C21orf55 Chromosome 21 open reading frame 55 741 1079 799 687 508 665
  BC001407   Similar to cytochrome c-like antigen 524 1004 629 506 502 577
  AK023104   FLJ22648 fis, clone HSI07329 441 984 621 488 471 495
  AK024617   FLJ20964 fis, clone ADSH00902 824 955 745 788 535 824
  BC009536   IMAGE:3892368 553 924 775 597 498 671
  AK056287   FLJ31725 fis, clone NT2RI2006716 435 862 907 405 459 893
  AK021611   FLJ11549 fis, clone HEMBA1002968 535 812 675 545 392 630
  BC015119   IMAGE:3951139 445 784 487 455 435 439
  AK056492   FLJ31930 fis, clone NT2RP7006162 252 651 525 266 367 457
  AB058711 KIAA1808 KIAA1808 protein 208 637 357 199 339 366
  BC011266   IMAGE:4156795 354 632 432 356 328 460
  AK023316   FLJ13254 fis, clone OVARC1000787 416 596 357 400 290 352
  NM_024696 FLJ23058 Hypothetical protein FLJ23058 456 541 346 436 313 359
  AF253316   Pheromone receptor (PHRET) pseudogene 136 520 425 128 301 347
  AK056007 BICD1 Bicaudal D homolog 1 (Drosophila) 704 505 439 624 243 305
  AB020632 KIAA0825 KIAA0825 protein 249 498 353 246 272 339
  NM_017609 DKFZp434A1721 Hypothetical protein DKFZp434A1721 182 485 319 190 298 304
  NM_018190 FLJ10715 Hypothetical protein FLJ10715 202 483 310 174 206 266
  AK057046   FLJ32484 fis, clone SKNMC2001555 229 473 294 261 302 228
  NM_013395 AD013 Proteinx0008 448 461 496 403 304 378
  BC008501 MGC14839 Similar to RIKEN cDNA 2310030G06 379 414 329 443 264 290
  AK021988   FLJ11926 fis, clone HEMBB1000374 321 411 399 280 218 288
  AF119872   PRO2272 257 405 327 257 205 250
  NM_022744 FLJ13868 Hypothetical protein FLJ13868 267 376 239 270 212 172
  AK022364   FLJ12302 fis, clone MAMMA1001864 172 355 316 164 184 332
  BC002644 MGC4859 Hypothetical protein MGC4859 similar to HSPA8 282 335 382 257 223 331
  AK022201   FLJ12139 fis, clone MAMMA1000339 267 302 152 235 123 131
  NM_017953 FLJ20729 Hypothetical protein FLJ20729 170 290 258 138 170 218
  AK057473   FLJ32911 fis, clone TESTI2006210 160 268 265 163 123 247
  U50383 RAI15 Retinoic acid induced 15 206 265 236 198 159 186
  AK027027   FLJ23374 fis, clone HEP16126 134 261 170 134 152 141
  AK057288   FLJ32726 fis, clone TESTI2000981 206 249 312 216 152 244
  U79280 PIPPIN Ortholog of rat pippin 274 229 189 238 117 134
  AK023628   FLJ13566 fis, clone PLACE1008330 140 195 230 133 128 193
  NM_025263 CAT56 CAT56 protein 126 194 147 127 101 130
  AF311324   Ubiquitin-like fusion protein 191 189 179 190 106 138
  NM_005708 GPC6 Glypican 6 107 185 144 109 88 146
  AB037778 KIAA1357 KIAA1357 protein 153 180 156 149 118 146
  AK055939   FLJ31377 fis, clone NESOP1000087 152 167 179 136 105 173
  NM_018316 FLJ11078 Hypothetical protein FLJ11078 89 145 118 73 94 103
  AF402776 BIC BIC noncoding mRNA 82 136 171 96 88 153
  BC003416   IMAGE:3450973 64 133 93 83 73 111
  AL137491   DKFZp434P1530 62 130 88 57 72 74
  AK057770   FLJ25041 fis, clone CBL03194 110 130 114 108 83 84
  AB058769 KIAA1866 KIAA1866 protein 89 126 122 102 83 91
  AB058747 WAC WW domain-containing adapter with a coiled-coil region 60 124 103 57 76 77
  AK054885 C6orf31 Chromosome 6 open reading frame 31 51 119 108 41 68 119
  AK022235   FLJ12173 fis, clone MAMMA1000696 109 103 94 90 62 77
  AK026853 AOAH Acyloxyacyl hydrolase (neutrophil) 59 98 64 59 61 56
  AK024877   FLJ21224 fis, clone COL00694 53 96 110 55 54 103
  NM_003171 SUPV3L1 Suppressor of var1, 3-like 1 (S. cerevisiae) 65 93 60 60 55 58
  NM_052933 TSGA13 Testis specific, 13 66 80 70 68 44 71
  AK057907   FLJ25178 fis, clone CBR09176 42 77 31 47 43 41
  AK055748   FLJ31186 fis, clone KIDNE2000335 88 67 68 79 44 71
  BC013757   IMAGE:4525041 40 54 39 43 33 32
  AL365511   Novel human gene mapping to chomosome 22 19 48 29 20 27 37
  AK026889 APRIN Androgen-induced proliferation inhibitor 31 35 42 34 21 34
  AK057423   FLJ32861 fis, clone TESTI2003589 36 32 34 30 18 31
  AK055543 MLSTD1 Male sterility domain containing 1 31 31 32 27 18 30
  AK056513   FLJ31951 fis, clone NT2RP7007177 33 29 20 22 13 20
  NM_013319 TERE1 Transitional epithelia response protein 22 28 19 24 17 22
  AK026456   FLJ22803 fis, clone KAIA2685 15 26 14 16 13 17
  AK021610   cDNA FLJ11548 fis, clone HEMBA1002944 34 26 29 31 15 28
  AK026823   FLJ23170 fis, clone LNG09984 15 22 14 19 8 18
  AK056805   FLJ32243 fis, clone PROST1000039 400 177 186 343 314 160
  NM_012238 SIRT1 Sirtuin silent mating type information regulation 2 homolog 1 (S. cerevisiae) 149 156 170 178 134 109
  NM_016099 GOLGA7 golgi autoantigen, golgin subfamily a, 7 10493 15165 9882 11947 11564 15698
  AK022482   FLJ12420 fis, clone MAMMA1003049 6052 9099 5803 6362 7620 9309
  AK026490 RAB32 RAB32, member RAS oncogene family 3677 7044 4641 3671 5553 7561
  NM_020684 NPD007 NPD007 protein 674 794 764 630 720 1215
  AL390158 ATXN7L3 Ataxin 7-like 3 319 460 378 339 403 598
  NM_017752 FLJ20298 Hypothetical protein FLJ20298 146 237 282 133 233 493
  AB037743 KIAA1322 KIAA1322 protein 236 202 199 239 246 319
  AF339819   clone IMAGE:38177 77 111 110 96 125 174
  AK055215   FLJ30653 fis, clone DFNES2000143 47 48 58 43 80 92