Histopathology profiles of guinea pig lung tissue sections after exposure to air or cigarette smoke in the presence and absence of black tea. Marked enlargement of airspaces was found in lung sections of the guinea pigs in the CS group (see 'Materials and Methods'). The number of guinea pigs used in each group was 4. Eight images were analyzed in 4 lung sections (2 images/section/animal) from each group (magnification ×10). In sharp contrast to the CS-exposed groups (CS group), the enlargement of airspace was greatly reduced in the CS+BT group. The number of air spaces analyzed and the morphometric measurements with statistical difference between the groups are shown in Table 1. A, air-exposed guinea pigs given water as the drink (sham control); B, CS-exposed guinea pigs given water as the drink; C, air-exposed guinea pigs given BT as the drink; D, CS-exposed guinea pigs given BT as the drink.