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Table 6 TNF-α expression in myocardial tissue.

From: Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease

Score

Cells Expressing TNF

Intensity of TNF Expression

Overall Score* (Cells Expressing × Intensity of Expression)

  

%

X ¯ MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaieqacuWFybawgaqeaaaa@2E03@

%

X ¯ MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaieqacuWFybawgaqeaaaa@2E03@

 

0 IF Placebo

1

0

0.00 ± 0.00

0

0.00 ± 0.00

0.00 ± 0.00c

 

2

0

 

0

  
 

3

0

 

0

  
 

4

0

 

0

  

126 IF Placebo

1

0

0.00 ± 0.00

0

0.00 ± 0.00

0.00 ± 0.00c

 

2

0

 

0

  
 

3

0

 

0

  
 

4

0

 

0

  

504 IF Placebo

1

0

0.00 ± 0.00

0

0.00 ± 0.00

0.00 ± 0.00c

 

2

0

 

0

  
 

3

0

 

0

  
 

4

0

 

0

  

0 IF LPS

1

12

2.88 ± 0.35

0

4.00 ± 0.00

11.50 ± 1.40a

 

2

12

 

0

  
 

3

50

 

0

  
 

4

25

 

100

  

126 IF LPS

1

33.3

1.67 ± 0.21

33.3

2.33 ± 0.56

4.33 ± 1.28b

 

2

66.6

 

33.3

  
 

3

0

 

0

  
 

4

0

 

33.3

  

504 IF LPS

1

71.4

2.00 ± 0.31

71.4

1.29 ± 0.18

2.86 ± 0.83b

 

2

28.6

 

28.6

  
 

3

0

 

0

  
 

4

0

 

0

  
  1. Mice were fed soy isoflavones (IF; 0, 126 or 504 mg aglycone equivalents of IF/kg diet) for 14-days prior to and during a 30-day exposure to LPS (1.33 μg/d). TNF-α expression was determined immunhistochemically. Chi-square analysis was performed on the % of cells expressing TNF-α and the intensity of expression. The overall score was calculated. Results for the overall score are expressed as means ± standard error. Values for a given parameter that share the same superscript letter are not statistically different (P > 0.05) from each other. P-value for LPS*Diet on overall scores is < 0.0001.