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Table 5 TNF-α expression in bone

From: Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease

Score Cells Expressing TNF-α Intensity of TNF-α Expression Overall Score* (Cells Expressing × Intensity of Expression)
   % X ¯ MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaieqacuWFybawgaqeaaaa@2E03@ % X ¯ MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaieqacuWFybawgaqeaaaa@2E03@  
0 IF Placebo 1 0 2.0 ± 0.3 0 2.0 ± 0.0 5.0 ± 0.6b
  2 50   100   
  3 50   0   
  4 0   0   
126 IF Placebo 1 33.3 1.7 ± 0.3 100 1.0 ± 0.0 1.7 ± 0.3c
  2 66.6   0   
  3 0   0   
  4 0   0   
504 IF Placebo 1 33.3 1.7 ± 0.3 100 1.0 ± 0.0 1.7 ± 0.3c
  2 66.6   0   
  3 0   0   
  4 0   0   
0 IF LPS 1 0 4.0 ± 0.0 0 4.0 ± 0.0 16.0 ± 0.0a
  2 0   0   
  3 0   0   
  4 100   100   
126 IF LPS 1 33.3 1.3 ± 0.3 33.3 1.7 ± 0.3 2.0 ± 0.0c
  2 66.6   66.6   
  3 0   0   
  4 0   0   
504 IF LPS 1 100 1.0 ± 0.0 33.3 1.7 ± 0.3 1.7 ± 0.3c
  2 0   66.6   
  3 0   0   
  4 0   0   
  1. Mice were fed soy isoflavones (IF; 0, 126 or 504 mg aglycone equivalents of IF/kg diet) for 14-days prior to and during a 30-day exposure to LPS (1.33 μg/d). TNF-α expression was determined immunhistochemically. Chi-square analysis was performed on the % of cells expressing TNF-α and the intensity of expression. The overall score was calculated. Results for the overall score are expressed as means ± standard error. Values for a given parameter that share the same superscript letter are not statistically different (P > 0.05) from each other. P-value for LPS*Diet on overall scores is < 0.0001.