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Table 3 Alterations in microarchitectural properties of cortical bone of the femur mid-diaphysis.

From: Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease

Treatment Cortical Thickness (μm) Cortical Area (mm2) Medullary Area (mm2) Porosity (%)
0 IF Placebo 0.187 ± 0.003 0.625 ± 0.001 0.010 ± 0.001 0.98 ± 0.28
0 IF LPS 0.197 ± 0.003 0.646 ± 0.010 0.010 ± 0.002 0.84 ± 0.20
126 IF Placebo 0.193 ± 0.002 0.628 ± 0.014 0.009 ± 0.001 1.07 ± 0.22
126 IF LPS 0.191 ± 0.003 0.625 ± 0.008 0.012 ± 0.002 1.08 ± 0.31
504 IF Placebo 0.194 ± 0.005 0.625 ± 0.014 0.010 ± 0.001 0.99 ± 0.24
504 IF LPS 0.198 ± 0.001 0.652 ± 0.011 0.009 ± 0.001 0.86 ± 0.22
P value     
LPS 0.1340 0.1086 0.4386 0.6895
IF 0.4189 0.5571 0.5553 0.7637
LPS*IF 0.1293 0.3899 0.1988 0.9444
  1. Mice were fed soy isoflavones (IF; 0, 126 or 504 mg aglycone equivalents of IF/kg diet; 0, Low or High, respectively) for 14-days prior to and during a 30-day exposure to LPS (1.33 μg/d). Results are expressed as means ± standard error.