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Table 3 Alterations in microarchitectural properties of cortical bone of the femur mid-diaphysis.

From: Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease

Treatment

Cortical Thickness (μm)

Cortical Area (mm2)

Medullary Area (mm2)

Porosity (%)

0 IF Placebo

0.187 ± 0.003

0.625 ± 0.001

0.010 ± 0.001

0.98 ± 0.28

0 IF LPS

0.197 ± 0.003

0.646 ± 0.010

0.010 ± 0.002

0.84 ± 0.20

126 IF Placebo

0.193 ± 0.002

0.628 ± 0.014

0.009 ± 0.001

1.07 ± 0.22

126 IF LPS

0.191 ± 0.003

0.625 ± 0.008

0.012 ± 0.002

1.08 ± 0.31

504 IF Placebo

0.194 ± 0.005

0.625 ± 0.014

0.010 ± 0.001

0.99 ± 0.24

504 IF LPS

0.198 ± 0.001

0.652 ± 0.011

0.009 ± 0.001

0.86 ± 0.22

P value

    

LPS

0.1340

0.1086

0.4386

0.6895

IF

0.4189

0.5571

0.5553

0.7637

LPS*IF

0.1293

0.3899

0.1988

0.9444

  1. Mice were fed soy isoflavones (IF; 0, 126 or 504 mg aglycone equivalents of IF/kg diet; 0, Low or High, respectively) for 14-days prior to and during a 30-day exposure to LPS (1.33 μg/d). Results are expressed as means ± standard error.