CD8+ T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis

Journal of Inflammation

Table 2 Analysis of the differential cell profile in BAL from study population, (n = 27)

Differential cell counts
Total BAL cell count ×10³/ml of recovered BAL^§	134.7 ± 13.6
Macrophages *	82.2 ± 2.7
Neutrophils *	6.8 ± 1.8
Eosinophils *	2.6 ± 0.6
Lymphocytes *	9.1 ± 1.9
Lymphocyte phenotypes
CD_2-/CD₁₉₊ cells **(B lymphocytes)	1.9 ± 0.3
CD₃₊/CD₁₆₊CD₅₆₊**(cytotoxic lymphocytes)	2.8 ± 0.5
CD_3-/CD₁₆₊CD₅₆₊ **(natural killer cells)	4 ± 0.6
CD₃₊ cells ** (TLs)	74.2 ± 4.6
CD₄₊ cells **(helper TLs)	35.8 ± 3. 9
CD₈₊ cells **(cytotoxic/suppressor TLs)	35.9 ± 3.9
CD_8+/38+ cells **(activated CD₈₊ cells) (n = 16)	4.0 ± 0.8
CD₄₊/CD₈₊ ratio	1.3 ± 0.2

Values are means ± SEM (with ranges in parentheses). ^§ The mean value of recovered BAL is 55.6% with a range of 41.6% to 80% *Values are expressed as percentages of total BAL cell count. ** Values are expressed as percentage of total lymphocytes.

ISSN: 1476-9255