Figure 1

Immunohistochemical Staining of Liver for ICAM-1 Expression. Positive ICAM-1 staining (brown color) is demonstrated in wild-type mice along the vasculature and sinusoids, but is notably absent in the P/I null mice. (A) Control, wild-type mouse, (B) Control, P/I null mouse, (C) Wild-type mouse after 90 minutes of ischemia and 6 h of reperfusion, (D) P/I null mouse after 90 minutes of ischemia and 6 h of reperfusion.