Table 1 Protein kinase C inhibitors, their specificity and IC50 values.
From: The tripeptide feG regulates the production of intracellular reactive oxygen species by neutrophils
Inhibitor (Selectivity) | IC50 Values | Concentration Used | Reference |
|---|---|---|---|
Gö6976 (α > β) | PKCα = 2 nM; PKCβ1 = 6 nM | 3 nM | [66, 67] |
Hispidin (β) | PKCβ = 3 μM | 6 μM | [68] |
Rottlerin (δ) | PKCδ = 2–6μ M; PKCα,β,γ = 30–40 μM | 6 μM | [51, 69] |