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Table 1 A summary of apoptosis induced in A549 cells by Taxol, Tobacco smoke condensate (TSC), paraldehyde (Para), nicotine, hydrogen peroxide (HP) and fresh cigarette smoke extract (CSE) as assessed by different markers of apoptosis. Ticks () show statistically significant increases from control cells (, p < 0.05; , p < 0.01; , p < 0.001), and crosses () indicate no change from control.

From: Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro

 

Taxol

TSC

Para

Nicotine

HP

100% CSE

50% CSE

Cell detachment (after 48 hrs)

Apoptotic morphology of detached cells (after 48 hours)

TUNEL on detached cells (after 24 hours)

Cytochrome C (after 4 hours)

Bax-α (after 4 hours)