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Table 1 The effects of RU24858, mometasone and dexamethasone on IL-5 induced human eosinophil survival. Apoptosis was analyzed by morphological criteria. Results are expressed as percentage of apoptotic cells. Values are the mean ± S.E.M., n = 6. * Indicates P < 0.05, ** P < 0.01, *** P < 0.001 as compared with the respective control in the absence of glucocorticoids.

From: The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils

  Apoptotic eosinophils (%)
  Control 1 nM IL-5 10 nM IL-5
control 43.3 ± 6.7 8.1 ± 1.5 9.3 ± 2.5
RU24858 1 μM 51.9 ± 5.5 * 11.6 ± 3.4 10.8 ± 3.8
Mometasone 1 μM 63.1 ± 6.8 *** 16.0 ± 2.9 ** 10.8 ± 3.6
Dexamethasone 1 μM 60.1 ± 4.4 ** 17.1 ± 3.3 ** 7.7 ± 2.6