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Table 1 Parameters of the model of diet-induced obesity.

From: Unaltered TNF-α production by macrophages and monocytes in diet-induced obesity in the rat

 

Short term diet (2 weeks)

Long term diet (10 weeks)

 

Chow

High Fat

Chow

High Fat

Caloric intake (cal/day)

95.6 ± 3.0

178.6 ± 19.1*

97.6 ± 11.3

229.9 ± 8.9*

Body weight (g)

287.5 ± 2.2

302.3 ± 5.0

515.6 ± 9.1

635.3 ± 12.3

White adipose tissue (g)

1.4 ± 0.1

2.7 ± 0.2 *

4.5 ± 0.4

12.4 ± 1.5*

Spleen (g)

0.88 ± 0.03

0.79 ± 0.02*

0.97 ± 0.04

0.89 ± 0.05

TNF-α (pg/ml)

5.9 ± 0.3

7.2 ± 0.9

ND

ND

  1. * p < 0.05 (high fat vs. chow fed); n = 9 for all groups
  2. ND = not detectable; detection limit 5.6 pg/ml