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Table 8 Sequential VAS – Pain Index

From: Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]

Group Baseline Week 1 Week 2 Week 4 Week 6 Week 8
Placebo 72.9 ± 2.1 71.4 ± 2.7 68.4 ± 3.2 63.9 ± 3.3 ** 58.6 ± 3.9 ** 52.0 ± 4.7 ***
A 72.9 ± 3.0 66.8 ± 3.3 62.5 ± 4.7 ** 51.2 ± 5.0 *** 49.7 ± 5.1 *** 42.7 ± 5.2 ***
B 70.1 ± 2.5 65.8 ± 3.2 58.9 ± 3.8 ** 52.0 ± 4.7*** 51.9 ± 5.0 *** 44.6 ± 4.9 ***
C 70.7 ± 2.4 65.0 ± 2.6 60.7 ± 2.9 ** 52.7 ± 2.5 *** 47.2 ± 3.4 *** 43.4 ± 3.8 ***
  1. Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using a Wilcoxan matched pairs Signed-Rank test from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.