Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]

Table 6 Sequential WOMAC C Scores – Physical Function

Group	Baseline	Week 1	Week 2	Week 4	Week 6	Week 8
Placebo	36.4 ± 3.9	37.0 ± 4.3	35.0 ± 4.4	32.0 ± 4.3	29.5 ± 4.5	26.6 ± 4.6 **
A	38.4 ± 4.9	32.4 ± 5.3	31.0 ± 5.1 **	26.1 ± 4.6 ***	26.3 ± 4.6 ***	23.1 ± 4.6 ***
B	34.7 ± 4.2	31.3 ± 4.4 *	28.7 ± 4.4 **	24.5 ± 3.8 ***	22.8 ± 3.9 ***	21.3 ± 2.9 ***
C	32.8 ± 4.3	31.1 ± 4.0	29.1 ± 4.0 *	24.3 ± 3.4 ***	21.7 ± 3.5 ***	19.7 ± 3.4 ***

Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using the Wilcoxan Matched-Pairs Signed-Rank test the following descriptors reflect statistical significance from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.

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