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Table 6 Sequential WOMAC C Scores – Physical Function

From: Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]

Group Baseline Week 1 Week 2 Week 4 Week 6 Week 8
Placebo 36.4 ± 3.9 37.0 ± 4.3 35.0 ± 4.4 32.0 ± 4.3 29.5 ± 4.5 26.6 ± 4.6 **
A 38.4 ± 4.9 32.4 ± 5.3 31.0 ± 5.1 ** 26.1 ± 4.6 *** 26.3 ± 4.6 *** 23.1 ± 4.6 ***
B 34.7 ± 4.2 31.3 ± 4.4 * 28.7 ± 4.4 ** 24.5 ± 3.8 *** 22.8 ± 3.9 *** 21.3 ± 2.9 ***
C 32.8 ± 4.3 31.1 ± 4.0 29.1 ± 4.0 * 24.3 ± 3.4 *** 21.7 ± 3.5 *** 19.7 ± 3.4 ***
  1. Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using the Wilcoxan Matched-Pairs Signed-Rank test the following descriptors reflect statistical significance from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.