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Table 5 Sequential WOMAC B Scores – Joint Stiffness

From: Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]

Group Baseline Week 1 Week 2 Week 4 Week 6 Week 8
Placebo 3.4 ± 0.5 3.6 ± 0.5 3.1 ± 0.5 3.0 ± 0.5 2.6 ± 0.5 * 2.4 ± 0.5 *
A 3.5 ± 0.5 3.0 ± 0.5 * 2.9 ± 0.6 * 2.4 ± 0.5 ** 2.4 ± 0.5 ** 2.3 ± 0.5 **
B 3.3 ± 0.4 2.9 ± 0.5 * 2.6 ± 0.5 ** 2.1 ± 0.4 ** 2.2 ± 0.5 ** 1.9 ± 0.3 **
C 3.3 ± 0.4 3.2 ± 0.4 3.0 ± 0.4 2.1 ± 0.3 *** 2.0 ± 0.3 *** 1.6 ± 0.4 ***
  1. Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using the Wilcoxan Matched-Pairs Signed-Rank test the following descriptors reflect statistical significance from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.