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Table 4 Sequential WOMAC A Scores – Pain

From: Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: A randomized controlled trial [ISRCTN38432711]

Group Baseline Week 1 Week 2 Week 4 Week 6 Week 8
Placebo 8.7 ± 1.0 8.9 ± 1.1 8.5 ± 1.2 8.4 ± 1.2 6.8 ± 1.1 * 6.3 ± 1.2 *
A 9.1 ± 1.2 8.1 ± 1.2 * 7.5 ± 1.2 ** 6.5 ± 1.2 ** 6.4 ± 1.2 ** 6.3 ± 1.1 **
B 8.0 ± 1.1 7.5 ± 1.1 6.9 ± 1.1 ** 5.7 ± 1.0 ** 5.6 ± 1.1 ** 5.0 ± 0.9 **
C 8.7 ± 1.0 8.0 ± 1.0b 6.9 ± 0.9 *** 5.6 ± 0.8 *** 5.0 ± 0.8 *** 4.3 ± 0.7 ***
  1. Data expressed as mean ± sem. Group A = High dose sierrasil (n = 20), Group B = Low dose sierrasil (n = 21), Group C = Low dose sierrasil + cat's claw extract (n = 25), placebo n = 22. All groups displayed a significant change over the 8 weeks of the study (p < 0.001, ANOVA). Using the Wilcoxan Matched-Pairs Signed-Rank test the following descriptors reflect statistical significance from baseline; * p < 0.05, ** p < 0.01, *** p < 0.001.