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Table 1 Ex vivo measurement of luciferase activity (Unit/μg protein). Selected organs were harvested from IkBα-luc mice that were untreated (control, n = 3) or treated with LPS (1 mg/kg, i.p., n = 3) at 4 hours prior to the harvesting.

From: Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

  Mean ± SE
  MALE FEMALE
ORGANS Control LPS Control LPS
Liver 157 ± 30 3651 ± 48*§ 157 ± 2 2933 ± 69*
Spleen 363 ± 69 6906 ± 878* 218 ± 58 6203 ± 1414*
Lungs 430 ± 112 3549 ± 291* 348 ± 52 2718 ± 452*
Intestine 89 ± 39 4640 ± 601* 73 ± 9 1367 ± 598*
Kidney 65 ± 7 709 ± 62* 67 ± 5 414 ± 26*
Heart 15 ± 2§ 951 ± 141* 7 ± 2 405 ± 8*
Brain 72 ± 13 513 ± 84* 73 ± 9 384 ± 52*
  1. *Difference from controls significant at P ≤ 0.05 by Mann-Whitney nonparametric test.