Skip to main content
Figure 2 | Journal of Inflammation

Figure 2

From: Combination therapy with ampicillin and azithromycin in an experimental pneumococcal pneumonia is bactericidal and effective in down regulating inflammation in mice

Figure 2

MPO activity of lung tissue of mice after intranasal administration of S. pneumoniae (AMRI-SP 1) followed by treatment with ampicillin or azithromycin alone or in combination. MPO activity was analyzed as index of neutrophil infiltration in the lung tissue. The rate of change in absorbance was measured spectrophotometrically at 405 nm. MPO activity has been defined as the concentration of enzyme degrading 1 μM of peroxide/min at 37°C and was expressed as change in absorbance/min. mg of protein. The results were reproduced in three repeated experiments. Data are expressed as mean ± SD of mice per group. P value less than 0.05 was considered as significant. *Significant decrease and #Significant increase at P < 0.05 level.

Back to article page

Journal of Inflammation

ISSN: 1476-9255

Contact us