Figure 1From: Combination therapy with ampicillin and azithromycin in an experimental pneumococcal pneumonia is bactericidal and effective in down regulating inflammation in miceEffect of combined antibiotic treatment on the survival of mice infected with S. pneumoniae (AMRI SP-1). Mice were challenged with a low dose of S. pneumoniae (5×106 CFU/mouse). Infected mice were treated with either AMP or AZM only or both in combination, 18 hours after infection (arrow: treatment regimen). The results (P < 0.05) of the survival analysis for groups of S. pneumoniae infected mice receiving either sterile saline (infected control) or antibiotic (n = 12 mice per experimental group and treatment regimen are indicated). AMP: Ampicillin treated; AZM: Azithromycin treated; Combination: AMP + AZM treated).Back to article page