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Figure 1 | Journal of Inflammation

Figure 1

From: Combination therapy with ampicillin and azithromycin in an experimental pneumococcal pneumonia is bactericidal and effective in down regulating inflammation in mice

Figure 1

Effect of combined antibiotic treatment on the survival of mice infected with S. pneumoniae (AMRI SP-1). Mice were challenged with a low dose of S. pneumoniae (5×106 CFU/mouse). Infected mice were treated with either AMP or AZM only or both in combination, 18 hours after infection (arrow: treatment regimen). The results (P < 0.05) of the survival analysis for groups of S. pneumoniae infected mice receiving either sterile saline (infected control) or antibiotic (n = 12 mice per experimental group and treatment regimen are indicated). AMP: Ampicillin treated; AZM: Azithromycin treated; Combination: AMP + AZM treated).

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