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Table 1 Change in gene expression profiles for genes that were uniquely expressed in BCM exposed HEKa cells after 2 hr of exposure

From: Early effects of Staphylococcus aureus biofilm secreted products on inflammatory responses of human epithelial keratinocytes

Gene symbol (function)

Fold-change BCM v Cont

Fold-change PCM v Cont

CXCL2 (inflammation)

15.082

-

IL8 (inflammation)

9.530

-

DUSP1 (inflammation/NO prod.)

9.061

-

IL6 (inflammation/NO prod.)

4.623

-

NFKBIA (inflammation)

4.093

-

EFNA1 (inflammation)

3.990

-

TNFAIP3 (inflammation)

3.964

-

ADM (inflammation/NO prod.)

2.917

-

CXCL1 (inflammation)

2.850

-

IL1B (inflammation/NO prod.)

2.586

-

ZFP36 (inflammation)

2.540

-

IFI27 (inflammation)

2.411

-

TNF (inflammation/NO prod.)

2.333

-

IL1A (inflammation/NO prod.)

2.113

-

PTGS2 (inflammation/NO prod.)

2.084

-

SMAD7 (inflammation)

2.073

-

IL20 (inflammation)

1.655

-

IL24 (inflammation)

1.540

-

MMP1 (inflammation)

-1.650

-

FOS (apoptosis)

8.433

-

ZC3H12A (apoptosis)

4.361

-

NR4A2 (apoptosis)

4.121

-

SGK1 (apoptosis)

3.045

-

CYP1B1 (apoptosis)

2.709

-

CYR61 (apoptosis)

2.587

-

BMP2 (apoptosis)

2.481

-

SLC25A24 (apoptosis)

2.467

-

CEBPD (apoptosis)

2.419

-

IFI27 (apoptosis)

2.411

-

BIRC3 (apoptosis)

1.643

-

HES1 (growth & proliferation)

4.280

-

DUSP10_v3 (growth & proliferation)

4.091

-

EFNA1 (growth & proliferation)

3.990

-

PPP1R15A (growth & proliferation)

3.582

-

JUN (growth & proliferation/NO prod.)

3.523

-

PPP1R10 (growth & proliferation)

3.099

-

HBEGF (growth & proliferation)

3.053

-

CYR61 (growth & proliferation)

2.587

-

CEBPD (growth & proliferation)

2.419

-

JUNB (growth & proliferation)

2.405

-

SMAD7 (growth & proliferation)

2.073

-

DUSP10_v1 (growth & proliferation)

1.764

-

CYR61 (wound healing)

2.587

-

  1. Genes identified through Illumina microarray results filtered to represent a 1.5 or greater fold change over the expression in the control sample.