Table 1 Patient characteristics
From: Prognostic value of endotoxin activity assay in patients with severe sepsis after cardiac surgery
Parameters | Overall population, n = 81 | Survivors, n = 44 | Non-survivors, n = 37 | p-value* | |
|---|---|---|---|---|---|
Age, years | 56 (47.5-64.5) | 53 (42–61) | 59 (52–66) | 0.06 | |
Male sex | 45/81 (56%) | 23/44 (52%) | 22/37 (59%) | 0.67 | |
APACHE II scores | 20 (10–30) | 11 (8–26) | 28 (15–31) | 0.0008 | |
Renal failure | 41/81 (50.6%) | 20/44 (45.5%) | 24/37 (64.9%) | 0.19 | |
Dialysis requirement | 19/81 (23.5%) | 6/44 (13.6%) | 13/37 (36.4%) | 0.44 | |
Epinephrine | Receivers | 74/81 (91.4%) | 40/44 (90.9%) | 34/37 (91.9%) | 0.81 |
Dose, mcg/kg/min | 0.08 (0.05-0.1) | 0.07 (0.05-0.1) | 0.09 (0.06-0.1) | 0.31 | |
Dopamine | Receivers | 53/81(65.4%) | 29/44 (65.9%) | 24/37 (64.9%) | 0.89 |
Dose, mcg/kg/min | 5 (4–7) | 5.5 (5–8) | 5 (3–6) | 0.06 | |
Dobutamine | Receivers | 26/81(32%) | 14/44(31.8%) | 11/37(29.7%) | 0.97 |
Dose, mcg/kg/min | 5.75 (4–8) | 5.15 (4.25-7) | 6 (4–8) | 0.64 | |
Norepinephrine | Receivers | 12/81(14.8%) | 5/44(11.4%) | 9/37(24.3%) | 0.02 |
Dose, mcg/kg/min | 0.07 (0.05-0.1) | 0.08 (0.05-0.15) | 0.06 (0.05-0.09) | 0.46 | |
WBC, х109/l | 13.2 (10.5-19.3) | 13 (10.6-20.8) | 13.4 (10–18.9) | 0.83 | |
LAL,EU/mL | 0.72 (0.36-0.72) | 0.72(0.36-0.72) | 0.72 (0.36-1.08) | 0.65 | |
РСТ, ng/mL | 5.07 (1.25-13.72) | 3.06 (0.72-8) | 5.69 (3.19-23.34) | 0.05 | |
ЕАА | 0.49 (0.39-0.66) | 0.45 (0.33-0.58) | 0.6 (0.45-0.69) | 0.009 | |