Figure 2From: TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivoTime course of pro-inflammatory cytokines in hearts of WT- and TLR2-D mice following LTA administration (15 mg/kg, i.p.). A, B: RT-qPCR of TNF-α and IL-1β Both cytokines revealed a significant increase in WT-mice after 2 h (*p < 0.05; n = 6; mean ± SEM). C, D: ELISA of TNF-α and IL-1β. LTA administration led to a significant increase in protein expression of both TNF-α and IL-1β in WT- but not TLR2-D mice with a maximum at 4 h (*p < 0.05; n = 6; mean ± SEM).Back to article page